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Anti-il21r Antibody (CAT#: MOM-18394)

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human il21r Antibody MOM-18394 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody is against Human IL21R, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • IL21R
  • Type
  • IgG
  • Immunogen
  • Rat YB2/0 hybridoma transfectant cell line expressing truncated Mouse IL21 Receptor
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, ICC and most other immunological methods.
  • Specific Activity
  • Tested positive against native antigen.
  • Purity
  • Purity >95% by SDS-PAGE.
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

BACKGROUND

  • Antigen Description
  • The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2 (IL2) and interleukin 5 (IL5). This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described.
  • Function
  • interleukin-21 receptor activity; receptor activity;
  • Synonyms
  • IL21R; interleukin 21 receptor; interleukin-21 receptor; CD360; IL-21R; IL-21 receptor; novel interleukin receptor; NILR; MGC10967

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